MOOD IMPROVE Mood Support Ingredients

This mood support supplement is a careful balance of the finest-quality organics and extracts that have real science behind their efficacy. Our clinical attention to preparation and quality guarantees maximum consistency, potency and results.

	B Vitamins: Scientific evidence continues to mount that B vitamins may ward off depression and other mental problems. A Finnish study found that high levels of vitamin B12 in the bloodstream were linked to more successful results amongst people being treated for depression. When researchers followed up with patients six months after sessions ended,those people with the highest B12 levels had the most success in addressing depression symptoms.
	Calcium: Calcium is central to the release of neurotransmitters and therefore directly involved in mood. Calcium deficiency causes nerve sensitivity, twitching muscles, palpitations, and mood and behavior disturbances including irritability, anxiety, depression, and insomnia.
	Chamomile: Chamomile is a member of the daisy family and has long been used as a relaxant. It is also known to have a calming effect on the central nervous system and has the ability to decrease anxiety. According to a study at the University of Pennsylvania in Philadelphia, treatment using chamomile extract reduced the symptoms of anxiety and depression. Chamomile contains a flavonoid called chrysin that helps to soothe anxiety symptoms in tests on rodents believed to be from its binding to benzodiazepine sites on GABA receptors.
	Magnesium: Magnesium is the fourth most abundant mineral in our bodies and, like calcium, it is involved in neurotransmitter release. It has been widely touted for its importance in many health areas, but particularly for mood support. In studies, researchers found a correlation between depression and lowered levels of magnesium and calcium. Tests indicated rapid recovery from major depression using just 100-300mg of magnesium, and some doctors believe it is likely that magnesium deficiency causes most major depression. Magnesium can: suppress the release of stress hormones is a necessary component for the release and uptake of serotonin (the happiness neurotransmitter) reduce the release of ACTH (the hormone that tells your adrenal glands to pump out cortisol and adrenaline) prevent the entrance of stress hormones into the brain
	Ashwagandha: Ashwagandha is a plant that has strong adaptogenic properties that help the body function optimally and bolster health. Studies suggest that ashwagandha may offer therapeutic benefit for dealing with stress and anxiety and the conditions associated with these disorders. Research suggests it may affect GABA receptors in a similar way as the pharmaceutical drugs Ativan and Valium (Cooley, Kieran, et al; PubMed: U.S. National Library of Medicine and the National Institutes of Health, August 31, 2009.)
	5-HTP: 5-HTP is a natural compound made in the body as serotonin is produced and is well accepted for its ability to regulate mood. Its ability to cross the blood-brain barrier (where serotonin cannot), makes it particularly effective for increasing serotonin levels and thereby influencing mood. Studies of 5-HTP in direct comparison to an SSRI (prescription antidepressant), showed it to be equivalently beneficial for depression, but with significantly fewer side effects. It is especially effective when combined with specific b vitamins and research shows it works well in concert with St Johns Wort.
	DMAE: DMAE is produced in the body in small quantities and is essential to the production of acetylcholine (helps nerve cells transmit signals). Studies demonstrated that DMAE can help alleviate chronic fatigue and mild depression through its effects on physical energy and motivation, especially by reducing apathy and increasing motivation (International Review of Neurobiology. 1959.) Researchers found that patients taking DMAE supplements had a greater increase in wellbeing than those who took the placebo.
	GABA: GABA is the neurotransmitter γ-aminobutyric acid (GABA), and considerable evidence implicates it in the biochemistry of mood disorders. It is the brain’s natural anxiety medication, regulating excitement in the central nervous system and brain by blocking certain transmissions between brain cells that induce agitation or anxiety. Research has confirmed that low levels of GABA are associated with mood disorders and depression. “Animal models of depression show regional brain GABA deficits and GABA agonists have antidepressant activity in these models in the biochemical pathophysiology of mood disorders.”
	St Johns Wort: St. John’s Wort has an over 2,000 year history of safe and effective traditional usage as a nerve tonic and has gained wide use recently as a mild antidepressant. Its action is based on the ability of the active ingredient, hypericin, to inhibit the breakdown of neurotransmitters in the brain. The herb also inhibits monoamine oxidase (MAO) and works as a serotonin reuptake inhibitor (SRI) — both actions similar to drugs typically prescribed for depression (British Med.J. 1996.) In Germany, nearly half of depression, anxiety, and sleep disorders are treated with hypericin.

Mood Support Supplement Usage

Check with your doctor before changing your regimen or if you are taking any prescribed drugs. MOOD IMPROVE works cumulatively and gradually over many weeks and should not necessarily be expected to provide immediate benefits. Because MOOD IMPROVE’s short-term effects can be extremely subtle, you may not notice changes for some weeks. The typical daily dose is 2 capsules, taken once in the morning and once in the evening 30 minutes before a meal. Since every person is unique, if you find no effect after 2 weeks, you may increase the dose. Do not exceed 4 capules per day. Check with your doctor and discuss appropriate dosage if you have questions.

Studies show that hypericum (St Johns Wort) can work to reduce symptoms of depression and anxiety immediately but often doesn’t show noticeable effects until 6-8 weeks of use, so MOOD IMPROVE may not reach maximum effectiveness for two months or more. This improvement will increase every month over six months (Fegert JM, Kölch M, Zito JM, Glaeske G, Janhsen K (2006). “Antidepressant use in children and adolescents in Germany”. J Child Adolesc Psychopharmacol 16 (1–2): 197–206. doi:10.1089/cap.2006.16.197.). It is recommended that it be taken for a minimum of 6 months, and can be considered a long term supplement as it can be safely taken continuously.

MOOD IMPROVE must be taken consistently for maximum effectiveness.

The speed of response varies greatly for each individual. On average, MOOD IMPROVE users first notice positive changes after three weeks, but some report improvement in less than a week while others experience benefits only after four or five weeks. For this reason, it’s important that you remain patient and not become discouraged if you don’t detect any changes during the first month.

The terms “depression”, “anxiety” and “panic” found on this website may refer to common emotions and should not be interpreted as referring to medically-recognized diseases. Statements about clinical research involving an ingredient in MOOD IMPROVE(MI) for the treatment of a disease should be considered only as background information about that ingredient. These statements do not represent a claim about the effects of MI itself and do not indicate that MI is intended to treat any disease or is a substitute for any drug. Statements that an ingredient found in MI has been proven in clinical trials to effectively treat a disease do not represent any claim regarding the effects of MI and do not indicate that MI itself has been proven to effectively treat that disease. MI is meant as a nutritional approach for those concerned with safety and health.

Mood Supplement Warnings

MOOD IMPROVE (MI) is completely natural and is safe for continuous use under normal circumstances. However, there are considerations when using MI, especially as many chemical and synthetic drugs will interfere with natural ingredients and vice versa. It is always recommended to consult with your physician prior to adding any supplement to your medication regimen. If you are on a prescription drug we recommend at very least leaving a 3-4 hour gap between taking any medications or supplements. Please check that St Johns Wort will not interact with your prescriptions.

Do not take if you are pregant, lactating, or have a heart condition. Check with your doctor before commencing any new supplement regime.

St. John’s Wort definitely increases your sensitivity to sunlight, which can be a minor problem for those of you who suntan frequently or must spend a great deal of time outdoors.

Here are some drug interaction concerns:

Antidepressants – St. John’s Wort may interact with antidepressant medications that are used to treat depression or other mood disorders, including tricyclics, SSRIs (see earlier discussion), and monoamine oxidase inhibitors (MAOIs) such as phenelzine. How St. John’s Wort works is not entirely clear, but is believed to be similar to how SSRIs work. Therefore, using St. John’s Wort with this class of antidepressants in particular can lead to exacerbation of side effects including headache, dizziness, nausea, agitation, anxiety, lethargy, and lack of coherence.

Digoxin – St. John’s Wort should not be taken by those on digoxin because the herb may decrease levels of the medication and reduce its effectiveness.

Immunosuppressive medications – St. John’s Wort should not be taken by those on immunosuppressive medications such as cyclosporine because it may reduce the effectiveness of these medications. In fact, there have been many reports of cyclosporin blood levels dropping in those with a heart or kidney transplant, even leading to rejection of the transplanted organ.

Indinavir and other protease inhibitors – The Food and Drug Administration (FDA) issued a public health advisory in February 2000 concerning the probable interaction between indinavir and St. John’s Wort that resulted in significantly decreased blood levels of this protease inhibitor, a class of medications used to treat HIV or AIDS. The FDA recommends that St. John’s Wort not be used with any type of antiretroviral medication used to treat HIV or AIDS.

Loperamide – There has been a report of a possible interaction between St. John’s Wort and the antidiarrheal medication, loperamide leading to delirium in an otherwise healthy woman.

Oral contraceptives – There have been reports of breakthough bleeding in women on birth control pills who were also taking St. John’s Wort.

Reserpine – Based on animal studies, St. John’s Wort may interfere with the intended action of this medication used to treat high blood pressure.

Theophylline – St. John’s Wort can reduce levels of this medication in the blood leading. Theophylline is used to open the airways in those suffering from asthma, emphysema, or chronic bronchitis.

Warfarin – St. John’s Wort interferes with the anticoagulant medication, warfarin, by reducing blood levels as well as the effectiveness. This leads to the need to for adjustments in doses of this medication.

Should I avoid any foods?

There has been much debate in this area recently, as it was believed that St. John’s Wort exhibits MAOI traits. If this is true, then people must avoid foods like red wine, alcohol in general, aged cheeses, sausage, etc. Doctors and researchers today believe that St. John’s Wort does not exhibit these properties, and therefore you need not be extremely concerned with the foods you eat. If you are concerned about this, consult your doctor and get a medical opinion.

The terms “depression”, “anxiety” and “panic” found on this website may refer to common emotions and should not be interpreted as referring to medically-recognized diseases. Statements about clinical research involving an ingredient in MOOD IMPROVE(MI) for the treatment of a disease should be considered only as background information about that ingredient. These statements do not represent a claim about the effects of MI itself and do not indicate that MI is intended to treat any disease or is a substitute for any drug. Statements that an ingredient found in MI has been proven in clinical trials to effectively treat a disease do not represent any claim regarding the effects of MI and do not indicate that MI itself has been proven to effectively treat that disease. MI is meant as a nutritional approach for those concerned with safety and health.